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Table 1 Tyrosinase inhibitory activity of the methanolic extract of E. bicyclis and its solvent fractions

From: Inhibitory effect of Fucofuroeckol-A from Eisenia bicyclis on tyrosinase activity and melanin biosynthesis in murine melanoma B16F10 cells

Samples IC50 (μg/mL)a
EtOH ex. 499.0 ± 6.6
n-hexane fr. > 1000
CH2Cl2 fr. 254.2 ± 0.3
EtOAc fr. 37.6 ± 0.1
n-BuOH fr. 82.4 ± 0.1
H2O fr. 514.9 ± 9.4
Arbutinb 299.3 ± 12.3
  1. aInhibition activity was expressed as 50% inhibitory concentration obtained by interpolation of the concentration inhibition %
  2. bArbutin was used as a positive control