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Table 1 Tyrosinase inhibitory activity of the methanolic extract of E. bicyclis and its solvent fractions

From: Inhibitory effect of Fucofuroeckol-A from Eisenia bicyclis on tyrosinase activity and melanin biosynthesis in murine melanoma B16F10 cells

Samples

IC50 (μg/mL)a

EtOH ex.

499.0 ± 6.6

n-hexane fr.

> 1000

CH2Cl2 fr.

254.2 ± 0.3

EtOAc fr.

37.6 ± 0.1

n-BuOH fr.

82.4 ± 0.1

H2O fr.

514.9 ± 9.4

Arbutinb

299.3 ± 12.3

  1. aInhibition activity was expressed as 50% inhibitory concentration obtained by interpolation of the concentration inhibition %
  2. bArbutin was used as a positive control
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Fisheries and Aquatic Sciences

ISSN: 2234-1757

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