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Fig. 1 | Fisheries and Aquatic Sciences

Fig. 1

From: A novel BACE inhibitor isolated from Eisenia bicyclis exhibits neuroprotective activity against β-amyloid toxicity

Fig. 1

Extraction and isolation procedure for E. bicyclis processing. a Steps to purify the active compound from the ethanol extract of E. bicyclis. To purify the active compound, liquid-liquid extraction, Sephadex LH-20 column chromatography, solid phase extraction (SPE) column chromatography, thin-layer chromatography (TLC), and high-performance liquid chromatography (HPLC) were used for the purification steps. b IC50 values (μg/mL) of the separated fractions from the purification steps of the active compound (Fr. B1-F1A). c Chromatograph of the purified active fraction (B1-F1A) from E. bicyclis by HPLC

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