Fig. 3From: Diversification and domain evolution of molluskan metallothioneins: a mini reviewMolecular phylogenetic tree (neighbor-joining tree drawn with MEGA7 (Kumar et al. 2016)) to propose the duplication of β1- (for P. coreanum MT) and β2-domain (A. irradians MT1 and MT2), giving rise to MTs with more than two metal-binding domains. Clades are visualized with the condensed tree cutoff value of 50% based on 1000 replicate bootstrap tests. For MT abbreviations and species, refer to Additional file 1: Table S1. Detailed domain structures of these multi-domain MTs are provided in Additional file 1: Figure S5BBack to article page