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Table 1 Bioassay of degradation activity of TEM-52 enzyme against various classes of antimicrobials

From: A novel method to depurate β-lactam antibiotic residues by administration of a broad-spectrum β-lactamase enzyme in fish tissues

Class Antimicrobials Inhibition zone (mm, mean ± SD)
Control drug disk TEM-52-treated drug disk
β-Lactam Cefotaxime 9.3 ± 0.6 0.0 ± 0.0
Cefazolin 6.0 ± 1.7 2.3 ± 1.2
Penicillin G 8.0 ± 0.6 0.0 ± 0.0
Amoxicillin 8.7 ± 0.6 0.0 ± 0.0
Pivampicillin 7.3 ± 0.6 0.0 ± 0.0
Tetracycline Oxytetracycline 9.8 ± 0.9 9.7 ± 0.6
Quinolone Ciprofloxacin 8.2 ± 0.0 8.0 ± 0.4
Macrolide Erythromycin 10.0 ± 1.0 10.0 ± 2.0
Josamycin 8.6 ± 0.6 8.7 ± 0.5
Aminoglycoside Streptomycin 8.5 ± 0.4 8.7 ± 0.6
  1. Concentrations of antimicrobials in incubation were adjusted to produce 6–11 mm clear zones beyond the disk areas (0.5–500 μg/disk)
  2. Triplicate determinations